This question concerns a pregnant woman who received mebendazole (Vermox) as a single dose in week

Fråga: This question concerns a pregnant woman who received mebendazole (Vermox) as a single dose in week 10 of pregnancy. The questioner asks if there are any documented teratogenic effects of mebendazole on the foetus.

Sammanfattning: Treatment with mebendazole has been reported to cause teratogenic effects in animal models. No evidence of teratogenic effects or malformations of the human foetus have been reported. A single dose treatment with mebendazole in week 10 is unlikely to increase the risk of malformations and is not an indication for abortion.

Svar: Similar questions have been answered several times previously by the Drug Information Centres. A follow-up Medline search did not add any new information. Generally, mebendazole treatment is not recommended because of teratogenic effects found in animal models (1). No teratogenic effects have been observed in humans, despite widespread use of the drug. It is therefore questionable whether the animal results are of any relevance for humans. 1 Drugline nr 09156 (year 1991)